The Future Looks Bright for Sickle Cell Anemia Research

I know I’ve said it before, but whatever, I’m saying it again: 2016 has been an awful year.

Both personally and globally, it’s been the total pits, to the point that I’m already planning on countering any complaint my future grandchildren make in life with, “At least you didn’t have to experience 2016.”

snow cold daria blizzard snowing
It’s going to be my generation’s version of “I walked uphill in the snow both ways.” Source: giphy.com

With that said, 2016 is almost over (thank God). As we approach 2017, we don’t know what will come, but the least we can do is welcome it with some good news.

While in so many other ways, the world has gone backwards, sideways, and completely off the rails this year, medical advancements continue at a steady, progressive pace.

Sickle cell anemia is one of the most recent conditions to benefit from such strides.

Passed through the recessive gene, sickle cell anemia is an inherited condition that  causes red blood cells to change shape, becoming rigid, sticky, and sickle-like (hence the name).

sickle cell anemia platelets
Here you can see some of the blood cells in that distinctive sickle shape. Source: flickr.com

These mutated cells can’t travel as easily, which results in blockages and less oxygen traveling through the body.

The condition can be painful, on top of the other complications that come with it.

Fortunately, at The Children’s Hospital of Philadelphia, researchers have made major gains for sickle cell anemia by exploring a technique known as “forced chromatin looping.”

The Jupital has a great scientific explanation of what researchers are trying to accomplish with this technique, but the short of it is, they may be able to restore functionality to the blood cells by producing foetal hemoglobin. This kind of hemoglobin (hemoglobin being the part of the blood cell that carries oxygen) isn’t affected by sickle cell.

The problem right now is that foetal hemoglobin doesn’t hang around much after birth. Hopefully with the new technique, researchers will find a way to restart that production in humans once they’ve aged.

This could be a big development for those living with sickle cell anemia.

I, for one, can’t wait to say goodbye to 2016 and move that much closer to a future where this research comes to its promised conclusion.

Read more about the research here.


Kiki Jones

Kiki Jones

Kiki’s family loves to say, “People are like a baking project. At some point, they’re just done and they’re who they’re going to be.” Well, Kiki still has some baking to do, and she learns a lot from her loved ones living with chronic conditions, including mental illness and Behcet’s disease. With a BA in English, she’s using her skills to tell the stories of people like them.

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