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Acquired Amegakaryocytic Thrombocytopenia

What is Acquired Amegakaryocytic Thrombocytopenia?

Acquired Amegakaryocytic Thrombocytopenia (AAT) is a rare blood disorder that causes severe thrombocytopenia (low blood platelet count) with no other blood abnormalities. Platlets, also called thrombocytes, assist in forming blood clots, they clump and form plugs in the blood vessel that will stop bleeding.

Worldwide, individuals of all racial and ethnic groups may be affected. Both males and females may be affected.

What are the symptoms of Acquired Amegakaryocytic Thrombocytopenia?

Common symptoms of Acquired Amegakaryocytic Thrombocytopenia include the following:
  • Prolonged bleeding
  • Easy bruising
  • Petechia, a rash with pinpoint red spots
  • Bleeding in the mouth and gums
  • Frequent nosebleeds

What causes Acquired Amegakaryocytic Thrombocytopenia?

AAT can be caused by any one of the following conditions: Pregnancy, Sensitivity to drugs, viral and bacterial infections, autoimmune diseases, exposure to environmental toxins and chemotherapy. AAT can be an early sign of more severe progressive diseases like leukemia, aplastic anemia, and myelodysplasia.

How is Acquired Amegakaryocytic Thrombocytopenia diagnosed?

AAT is usually diagnosed due to the very character of the symptoms. Testing such as, complete blood count, blood smear, clotting studies and bone marrow tests will be used to confirm the diagnosis.

What are the treatments for Acquired Amegakaryocytic Thrombocytopenia?

AAT does not have established standard treatment guidelines. Immunosuppressive treatment approaches have been utilized in affected people.

Where can I find out more about Acquired Amegakaryocytic Thrombocytopenia?

Acquired Amegakaryocytic Thrombocytopenia Articles