Does Brain Inflammation Play a Role in Alzheimer’s Disease?
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Does Brain Inflammation Play a Role in Alzheimer’s Disease?

Neurogeneticist Michael Nalls of the US National Institute on Aging recently told Science Alert that a 2022 study, published in the Journal of Alzheimer’s Disease, completely changed their discovery approach.…

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Alzheimer’s: A Neuroscientist at the OHSU Claims Scientists Missed a Major Form of Cell Death
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Alzheimer’s: A Neuroscientist at the OHSU Claims Scientists Missed a Major Form of Cell Death

Ferroptosis, a form of cell death, destroys microglia cells, which are associated with the brain’s immune system in vascular dementia and Alzheimer’s. Dr. Stephen Back suggested that attention had not…

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Alzheimer’s: Another Drug Failure Has the Researchers Questioning the Science
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Alzheimer’s: Another Drug Failure Has the Researchers Questioning the Science

  Roche has added another failure this year with its drug gantenerumab. As noted in Fierce Biotech, the drug was unable to improve functional or cognitive decline in two Phase…

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November was Alzheimer’s Awareness Month
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November was Alzheimer’s Awareness Month

  The need for increased awareness about Alzheimer’s disease is growing. The number of Alzheimer’s patients has increased since 1983, the year President Reagan designated November as Alzheimer’s Disease Awareness…

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New Podcast Episode: Going All In On Support, feat. Patient Advocates Kathi and Dave Herzog
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New Podcast Episode: Going All In On Support, feat. Patient Advocates Kathi and Dave Herzog

We are excited to announce that Patient Worthy's award-winning podcast "Wait, How Do You Spell That? A Rare Disease Podcast" is back with a new episode. This week, Colby is…

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Scientists Demonstrate Gut Microbiome Connection with Transfer of Alzheimer’s to Healthy Animals
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Scientists Demonstrate Gut Microbiome Connection with Transfer of Alzheimer’s to Healthy Animals

  Scientists have previously suggested that the gut microbiome plays a role in causing Alzheimer’s disease, and this has now been confirmed. A recent report from ScienceAlert covered a study…

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AI Can Predict Dementia Fifteen Years Prior to Symptoms Occurring
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AI Can Predict Dementia Fifteen Years Prior to Symptoms Occurring

Editor's Note: We believe that patients are a key part of developing and leading the conversation in disease communities. Patient Worthy sometimes partners with reputable agencies that wish to speak…

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FDA Panel Backs Approval of a New Drug for Alzheimer’s
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FDA Panel Backs Approval of a New Drug for Alzheimer’s

  The FDA advisory panel which is composed of specialists who advise the FDA on brain medications, recently voted 6-0 in agreement on that the new drug, Leqembi, was effective…

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Study of the Week: A Device That Can Detect Alzheimer’s 17 Years Before Symptoms Start
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Study of the Week: A Device That Can Detect Alzheimer’s 17 Years Before Symptoms Start

Welcome to Study of the Week from Patient Worthy. In this segment, we select a study we posted about from the previous week that we think is of particular interest…

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Editor’s Choice: A Biomarker for Early Alzheimer’s Detection, A Teen Living with Usher Syndrome, and A Possible Chagas Disease Treatment

Happy Monday! This week, we have details on a method for detecting Alzheimer's 17 years in advance, the story of a teen living with Usher syndrome, and a possible breakthrough…

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Alzheimer’s Disease: Study Suggests a Connection Between Digestive Disorders and AD
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Alzheimer’s Disease: Study Suggests a Connection Between Digestive Disorders and AD

  The gut-brain axis has recently been mentioned in connection with various disorders. According to an article in SciTechDaily, a study at ECU’s Centre for Precision Health confirms a genetic…

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Alzheimer’s: German and UK Scientists Successfully Reduced Alzheimer’s Symptoms in Laboratory Animals

  Eureka Alert recently published a statement by a team of researchers that early results of a new method of treating Alzheimer’s have been “absolutely spectacular.” The new antibody-based therapy…

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Alzheimer’s: A 50-year-old FDA Approved Diuretic Restored Normal Brain Activity in Mice; Will It Work On Humans?
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Alzheimer’s: A 50-year-old FDA Approved Diuretic Restored Normal Brain Activity in Mice; Will It Work On Humans?

  When you are looking for new treatments that will either stop or slow the development of Alzheimer’s disease, where would you look? According to a recent article in Gladstone…

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 Scientists Announce Breakthrough Discovery for Alzheimer’s and Other Neurological Diseases
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 Scientists Announce Breakthrough Discovery for Alzheimer’s and Other Neurological Diseases

   The Times Now News recently featured an article that highlighted a study by a group of NYU Langone scientists. The study paper was published October 6th, 2021 in the…

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Two Decades of Research May Be Reversed by a New Alzheimer’s Discovery
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Two Decades of Research May Be Reversed by a New Alzheimer’s Discovery

Alois Alzheimer, a clinical psychiatrist and expert in the study of the nervous system, reported a disease process of the cerebral cortex. The year was 1906. We are approaching July…

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Biogen’s Newly Approved Alzheimer’s Drug Ships in 2 Weeks. The Confirmatory Trial Will Take 8 Years.
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Biogen’s Newly Approved Alzheimer’s Drug Ships in 2 Weeks. The Confirmatory Trial Will Take 8 Years.

  The pressure was on. Researchers had been studying Alzheimer’s for decades. Every morsel of discovery was hailed as moving closer to a cure and results were always expected soon…

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FDA Approves New Alzheimer’s Drug, But Not Without Controversy
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FDA Approves New Alzheimer’s Drug, But Not Without Controversy

According to an announcement from the US Food and Drug Administration (FDA), the agency has recently approved a new therapy for Alzheimer's disease. While this is a significant moment for…

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Light Therapy: A Safe, Effective, and Low-Cost Approach to Some Neurodegenerative Diseases

In the last decade, scientists have made great strides in uncovering details of the underlying causes of neurodegenerative diseases. It is only a matter of time that treatment and prevention…

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LX1001 for APOE4-Associated Alzheimer’s Granted Fast Track Designation
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LX1001 for APOE4-Associated Alzheimer’s Granted Fast Track Designation

  In a recent press release, biotechnology and gene therapy company LEXEO Therapeutics ("LEXEO") shared that its gene therapy LX1001 received Fast Track designation from the FDA. Overall, LX1001 is…

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A First: Human Clinical Trial Assessing Gene Therapy for Alzheimer’s Disease
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A First: Human Clinical Trial Assessing Gene Therapy for Alzheimer’s Disease

Billions of dollars have been spent in research over decades, resulting in only two therapies that treat symptoms of Alzheimer’s disease (AD). There are no approved methods that diminish the…

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Five Genes Identified That May Cause Lewy Body Dementia
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Five Genes Identified That May Cause Lewy Body Dementia

According to a recent press release, scientists studying the Uniformed Services University of the Health Sciences' (USU) The American Genome Center (TAGC) identified five genes which could play a role…

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Each New Discovery Brings Scientists Closer to Finding the Cause of Alzheimer’s Disease
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Each New Discovery Brings Scientists Closer to Finding the Cause of Alzheimer’s Disease

Scientists are researching Alzheimer’s disease (AD) from all angles and gradually closing in on the cause of the disease. According to an article in Neuroscience News, a discovery by researchers…

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