Certain Antibiotics Associated with Higher GvHD Risk Following Allo-HCT
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Certain Antibiotics Associated with Higher GvHD Risk Following Allo-HCT

  Following allogeneic hematopoietic stem cell transplant (allo-HCT), which uses healthy stem cells from a donor, many doctors prescribe antibiotics to patients as a protective measure. Many individuals become neutropenic…

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AltruBio’s Dr. Jesse Hall Discusses Data on ALTB-168 for Acute GvHD
Photo Courtesy of Dr. Jesse W. Hall

AltruBio’s Dr. Jesse Hall Discusses Data on ALTB-168 for Acute GvHD

The American Society of Hematology (ASH) held its 64th Annual Meeting from December 10-13, 2022. During the meeting, doctors, researchers, and other stakeholders within the hematology sphere came together to…

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Thousands of Children are Waiting for FDA’s Approval of IMBRUVICA for Pediatric Graft-Versus-Host Disease
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Thousands of Children are Waiting for FDA’s Approval of IMBRUVICA for Pediatric Graft-Versus-Host Disease

  Every year almost half of the fourteen thousand patients who have received bone marrow or stem cell transplants will develop chronic graft-versus-host disease (cGVHD). Currently, there are no options…

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The FDA Rejects New Drug for SR-aGVHD, Shocking Scientists and Patients
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The FDA Rejects New Drug for SR-aGVHD, Shocking Scientists and Patients

As reported in BioSpace, the FDA shocked Mesoblast executives, a stem-cell research company, when this October, they rejected the Biologics License Application (BLA) for the drug Ryoncil, meant to treat…

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Massachusetts General Cancer Center Receives the First Incyte Ingenuity Award for GvHD
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Massachusetts General Cancer Center Receives the First Incyte Ingenuity Award for GvHD

The global biopharmaceutical company Incyte recently announced the first-ever recipient of its Incyte Ingenuity Award, which will be the Massachusetts General Cancer Center (MGCC). The purpose of this award is…

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COVID-19 Patients Were Removed From Ventilators Within Ten Days After Two Infusions of Ryoncil
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COVID-19 Patients Were Removed From Ventilators Within Ten Days After Two Infusions of Ryoncil

  A recent article in Biospace reported an 83% survival rate for COVID-19 patients after two infusions of the experimental drug Ryoncil, developed by Mesoblast Ltd. The patients who were…

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Stem Cell Therapy Using Patient’s Own Cells Shows Potential for Chronic Granulomatous Disease
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Stem Cell Therapy Using Patient’s Own Cells Shows Potential for Chronic Granulomatous Disease

Chronic granulomatous disease (CGD) is a rare form of immunodeficiency. The most common form of this disease is X-linked chronic granulomatous disease (X-CGD) which is caused by a mutated CYBB gene. This…

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Biotech Companies are Increasingly Focused on Deadly Diseases With Significant Unmet Need

According to a story from finanznachrichten.de, biotechnology companies are starting to set their sights on treating deadly diseases that are lacking effective treatment options, including some diseases that are considered…

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Interim Data for Phase 3 Graft-versus-Host Disease Trial Looks Promising

According to a story from PR Newswire, the specialty pharmaceutical company Mallinckrodt plc recently announced the release of interim data from the company's Phase 3 clinical trial. This trial is…

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Researchers Discover Causes of Graft-Verus-Host-Disease
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Researchers Discover Causes of Graft-Verus-Host-Disease

Research into graft-versus-host-disease (GVHD), a condition that can occur after bone marrow transplants, has yielded promising results. A study, reported by BrightSurf, found that a particular group of microRNA molecules involved…

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