{"id":111638,"date":"2018-01-01T16:30:23","date_gmt":"2018-01-01T21:30:23","guid":{"rendered":"https:\/\/patientworthy.wpengine.com\/2018\/01\/01\/gene-modifying-therapy-important-new-breakthrough\/"},"modified":"2018-12-11T11:12:01","modified_gmt":"2018-12-11T16:12:01","slug":"terapia-de-modificacion-genetica-tiene-un-nuevo-avance-importante","status":"publish","type":"post","link":"https:\/\/patientworthy.com\/es\/2018\/01\/01\/terapia-de-modificacion-genetica-tiene-un-nuevo-avance-importante\/","title":{"rendered":"Terapia de modificaci\u00f3n gen\u00e9tica tiene un nuevo avance importante"},"content":{"rendered":"<p>Uno de los recientes desarrollos mas grandes en el campo de la investigaci\u00f3n m\u00e9dica, en los \u00faltimos 5 a\u0148os! &#8211; Es una forma de\u00a0<a href=\"https:\/\/ghr.nlm.nih.gov\/primer\/genomicresearch\/genomeediting\">gene editing,<\/a>\u00c2\u00a0also know as genome editing.<\/p>\n<h3>La edici\u00f3n gen\u00e9tica se refiere a tecnolog\u00edas que le da la capcidad a cient\u00edficos de cambiar el ADN de un organismo.<\/h3>\n<p>Estas technolog\u00edas permiten la agregaci\u00f3n, eliminaci\u00f3n y modificaci\u00f3n de material gen\u00e9tico en posiciones espec\u00edficas.<\/p>\n<p>Se han desarrollado varios enfoques para la edici\u00f3n del genoma que incluyen repeticiones palindr\u00f3micas cortas y agrupadas, regularmente espaciadas y la prote\u00edna asociada a CRISPR 9, or CRISPR-Cas9.<\/p>\n<h3>El sistema CRISPR-Cas9 ha generado mucha expectaci\u00f3n en la comunidad cient\u00edfica porque es m\u00e1s r\u00e1pido, m\u00e1s econ\u00f3mico, m\u00e1s preciso y m\u00e1s eficiente que otros m\u00e9todos de edici\u00f3n de genoma existentes.<\/h3>\n<p>Si bien su potencial es inquestionable &#8211; <a href=\"https:\/\/www.fastcompany.com\/40426601\/the-ethics-of-crispr\" target=\"_blank\" rel=\"noopener\">lost temas de \u00e9tica y segurida <\/a> han prevenido que CRISPR sea utilizado para tratamiento de enfermedades en humanos. Estas preocupaciones \u00e9ticas incluyen principalment la capacidad the editar embriones humanos.<\/p>\n<h3>Sin embargo, CRISPR\/Cas9 se est\u00e1 estudiando en el Instituto Salk para el tratamiento de la diabetes, condiciones renales y distrofia muscular en ratones, <em>sin<\/em> editar el ADN.<\/h3>\n<p>Este m\u00e9todo implica que evitan las multaciones no deseadas, trabajan epigen\u00e9ticamente &#8211; o influyen en la actividad del gen sin cambiar la secuencia de ADN.<\/p>\n<p>El Instituto Salk prepar\u00f3 \u00e9ste video <a href=\"https:\/\/www.youtube.com\/watch?v=nf9jmqcWqns\" target=\"_blank\" rel=\"noopener\">video <\/a>to explain!<\/p>\n<h4>And the studies seem to be working!<\/h4>\n<div id=\"yui_3_14_1_1_1513004234863_707\" class=\"post-body\">\n<div id=\"yui_3_14_1_1_1513004234863_706\">\n<p>El tratamiento fu\u00e9 efective en disminuir los niveles de glucosa en la sangre, en enfermedad renal aguda, y en en el tratamiento de una forma de distrofia muscular.<\/p>\n<p>Presione aqu\u00ed <a href=\"https:\/\/www.researchgate.net\/blog\/post\/crispr-modification-overcomes-major-hurdle-to-human-treatments\">here <\/a>para leer una entrevista con\u00a0Juan Carlos Izpisua Belmonte\u00c2\u00a0del Laboratory de Expresi\u00f3n de Genes, sobre nuevos desarrollos!<\/p>\n<hr \/>\n<h4 class=\"footer-text\" style=\"text-align: center;\">What are your thoughts about CRISPR? <a href=\"https:\/\/patientworthy.com\/submit\/\">Share your thoughts, and your hopes, with the Patient Worthy community!<\/a><\/h4>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Uno de los recientes desarrollos mas grandes en el campo de la investigaci\u00f3n m\u00e9dica, en los \u00faltimos 5 a\u0148os! &#8211; Es una forma de\u00a0gene editing,\u00c2\u00a0also know as genome editing. La edici\u00f3n gen\u00e9tica se refiere a tecnolog\u00edas que le da la capcidad a cient\u00edficos de cambiar el ADN de un organismo. Estas technolog\u00edas permiten la agregaci\u00f3n, [&hellip;]<\/p>\n","protected":false},"author":107,"featured_media":111639,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"ocean_front_end_style_editor":"no","ocean_post_layout":"","ocean_both_sidebars_style":"","ocean_both_sidebars_content_width":0,"ocean_both_sidebars_sidebars_width":0,"ocean_sidebar":"0","ocean_second_sidebar":"0","ocean_disable_margins":"enable","ocean_add_body_class":"","ocean_shortcode_before_top_bar":"","ocean_shortcode_after_top_bar":"","ocean_shortcode_before_header":"","ocean_shortcode_after_header":"","ocean_has_shortcode":"","ocean_shortcode_after_title":"","ocean_shortcode_before_footer_widgets":"","ocean_shortcode_after_footer_widgets":"","ocean_shortcode_before_footer_bottom":"","ocean_shortcode_after_footer_bottom":"","ocean_display_top_bar":"default","ocean_display_header":"default","ocean_header_style":"","ocean_center_header_left_menu":"0","ocean_custom_header_template":"0","ocean_custom_logo":0,"ocean_custom_retina_logo":0,"ocean_custom_logo_max_width":0,"ocean_custom_logo_tablet_max_width":0,"ocean_custom_logo_mobile_max_width":0,"ocean_custom_logo_max_height":0,"ocean_custom_logo_tablet_max_height":0,"ocean_custom_logo_mobile_max_height":0,"ocean_header_custom_menu":"0","ocean_menu_typo_font_family":"0","ocean_menu_typo_font_subset":"","ocean_menu_typo_font_size":0,"ocean_menu_typo_font_size_tablet":0,"ocean_menu_typo_font_size_mobile":0,"ocean_menu_typo_font_size_unit":"px","ocean_menu_typo_font_weight":"","ocean_menu_typo_font_weight_tablet":"","ocean_menu_typo_font_weight_mobile":"","ocean_menu_typo_transform":"","ocean_menu_typo_transform_tablet":"","ocean_menu_typo_transform_mobile":"","ocean_menu_typo_line_height":0,"ocean_menu_typo_line_height_tablet":0,"ocean_menu_typo_line_height_mobile":0,"ocean_menu_typo_line_height_unit":"","ocean_menu_typo_spacing":0,"ocean_menu_typo_spacing_tablet":0,"ocean_menu_typo_spacing_mobile":0,"ocean_menu_typo_spacing_unit":"","ocean_menu_link_color":"","ocean_menu_link_color_hover":"","ocean_menu_link_color_active":"","ocean_menu_link_background":"","ocean_menu_link_hover_background":"","ocean_menu_link_active_background":"","ocean_menu_social_links_bg":"","ocean_menu_social_hover_links_bg":"","ocean_menu_social_links_color":"","ocean_menu_social_hover_links_color":"","ocean_disable_title":"default","ocean_disable_heading":"default","ocean_post_title":"","ocean_post_subheading":"","ocean_post_title_style":"","ocean_post_title_background_color":"","ocean_post_title_background":0,"ocean_post_title_bg_image_position":"","ocean_post_title_bg_image_attachment":"","ocean_post_title_bg_image_repeat":"","ocean_post_title_bg_image_size":"","ocean_post_title_height":0,"ocean_post_title_bg_overlay":0.5,"ocean_post_title_bg_overlay_color":"","ocean_disable_breadcrumbs":"default","ocean_breadcrumbs_color":"","ocean_breadcrumbs_separator_color":"","ocean_breadcrumbs_links_color":"","ocean_breadcrumbs_links_hover_color":"","ocean_display_footer_widgets":"default","ocean_display_footer_bottom":"default","ocean_custom_footer_template":"0","ocean_post_oembed":"","ocean_post_self_hosted_media":"","ocean_post_video_embed":"","ocean_link_format":"","ocean_link_format_target":"self","ocean_quote_format":"","ocean_quote_format_link":"post","ocean_gallery_link_images":"off","ocean_gallery_id":[]},"categories":[12077,12070,12074,12007],"tags":[12075,12078,12067,12076,12068,14398],"_links":{"self":[{"href":"https:\/\/patientworthy.com\/es\/wp-json\/wp\/v2\/posts\/111638"}],"collection":[{"href":"https:\/\/patientworthy.com\/es\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/patientworthy.com\/es\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/patientworthy.com\/es\/wp-json\/wp\/v2\/users\/107"}],"replies":[{"embeddable":true,"href":"https:\/\/patientworthy.com\/es\/wp-json\/wp\/v2\/comments?post=111638"}],"version-history":[{"count":0,"href":"https:\/\/patientworthy.com\/es\/wp-json\/wp\/v2\/posts\/111638\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/patientworthy.com\/es\/wp-json\/wp\/v2\/media\/111639"}],"wp:attachment":[{"href":"https:\/\/patientworthy.com\/es\/wp-json\/wp\/v2\/media?parent=111638"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/patientworthy.com\/es\/wp-json\/wp\/v2\/categories?post=111638"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/patientworthy.com\/es\/wp-json\/wp\/v2\/tags?post=111638"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}