Vitreoretinal Lymphoma (VRL)

What is vitreoretinal lymphoma?

Vitreoretinal lymphoma (VRL) is a rare form of non-Hodgkin lymphoma that impacts the eyes. It may also be called primary intraocular lymphoma. It most commonly impacts females in their 50’s and 60’s. 

What are the symptoms of vitreoretinal lymphoma?

Common symptoms include: 

• Blurred vision
• Floaters
• Red eyes
• Painless vision loss
• Photophobia 

What causes vitreoretinal lymphoma?

Medical professionals are unsure of the cause of this cancer. They do know that being of older age (age 50 and above) raises the risk of VRL. 

How is vitreoretinal lymphoma diagnosed?

It can be very difficult to get a proper diagnosis for this cancer, as it mimics chronic uveitis. In order to come to the correct diagnosis, doctors will use ophthalmic imaging studies, eye biopsies, and other lab tests to rule out other conditions. 

What are the treatments for vitreoretinal lymphoma?

Doctors will often use one of or a combination of radiotherapy, systemic therapy, and intravitreal chemotherapy to treat VRL. 

Where can I find out more about vitreoretinal lymphoma?

• • American Academy of Ophthalmology 
  • NIH
  • New York Eye Cancer Center