Could Gemini Track Multiple Myeloma Disease Progression?

 

Although we may feel like the world is stopped, thanks to COVID-19, many companies consistently push for technological advances. According to Myeloma Research News, GNS Healthcare is one of those companies. They created a computer program called Gemini which can model and predict treatment responses and disease progression for multiple myeloma. Now, GNS hopes to change the healthcare field – and the understanding of multiple myeloma – using this in-depth technological resource.

Gemini

Altogether, the full name for the program is Gemini, the in silico “Patient.” It was developed through a collaboration between GNS Healthcare, other biopharmaceutical companies and medical centers, and the Multiple Myeloma Research Foundation (MMRF). Although the name sounds a bit complicated, it isn’t! According to the Marshall Protocol Knowledge Base (MPKB), il silico:

is an expression used to mean “performed on computer or via computer simulation.” The expression in silico was first used [by] Pedro Miramontes, [who] used the term “in silico” to characterize biological experiments carried out entirely in a computer.

Within Gemini is a ton of data regarding multiple myeloma treatments, survival rates, disease progression, and patient outcomes. Additionally, the data follows that from the CoMMpass Study, which follows patients over a period of several years.

Next, researchers used artificial intelligence to analyze data. As a result, Gemini is able to create connections between different data sets.

Using these connections, Gemini then predicts disease progression and treatment efficacy using new patient data. Moving forward, the program can:

  • Identify patients for clinical trials who are most likely to respond to treatment or benefit from experimental treatment options
  • Predict and model patient outcomes without subjecting patients to potentially harmful treatments
  • Determine effective treatment order

Multiple Myeloma

Researchers note that in many cases of multiple myeloma, patients are missing part (or all) of chromosome 13. Multiple myeloma develops in plasma cells, a type of white blood cell that usually fights infections. But when abnormal cells replicate, they crowd out healthy cells, creating abnormal antibodies.

Symptoms include:

  • Nausea
  • Kidney problems
  • Constipation
  • Appetite loss
  • Spine and chest pain
  • Fatigue
  • Confusion
  • Unintended weight loss
  • Leg weakness

Learn more about multiple myeloma here.


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