What is Acitretin Embryopathy?
Acitretin embryopathy has been known only in fetuses and the cause of this disease is a teratogenic disorder. this disorder is due to to acitretin or etretinate exposure during the first trimester of pregnancy, which leads to risk of fetal malformations.
Acitretin/Etretinate embryopathy is a teratogenic disorder due to acitretin or etretinate exposure during the first trimester of pregnancy, carrying a risk of fetal malformations of approximately 20%, including central nervous system, craniofacial, ear, thymic, cardiac and limb anomalies.
What are the symptoms of Acitretin Embryopathy?Common symptoms of Acitretin Embryopathy include the following:
- 20% malformations of fetal including central nervous system
- Ear abnormalities
- Thymic and cardiac defects
- Limb irregularities
- Cup-shaped ears