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Acitretin Embryopathy

What is Acitretin Embryopathy?

Acitretin embryopathy has been known only in fetuses and the cause of this disease is a teratogenic disorder. this disorder is due to to acitretin or etretinate exposure during the first trimester of pregnancy, which leads to risk of fetal malformations.

Acitretin/Etretinate embryopathy is a teratogenic disorder due to acitretin or etretinate exposure during the first trimester of pregnancy, carrying a risk of fetal malformations of approximately 20%, including central nervous system, craniofacial, ear, thymic, cardiac and limb anomalies.

What are the symptoms of Acitretin Embryopathy?

Common symptoms of Acitretin Embryopathy include the following:
  • 20% malformations of fetal including central nervous system
  • Craniofacial
  • Ear abnormalities
  • Thymic and cardiac defects
  • Limb irregularities
  • Cup-shaped ears

What causes Acitretin Embryopathy?

This disorder is due to to acitretin or etretinate exposure during the first trimester of pregnancy.

How is Acitretin Embryopathy diagnosed?

Family and medical history, especially the use of Acitretin during the first trimester of pregnancy. Ultrasound can also be used during pregnancy to confirm diagnosis.

What are the treatments for Acitretin Embryopathy?

Treatment consists of managing the symptoms for each individual patient.

Where can I find out more about Acitretin Embryopathy?

Acitretin Embryopathy Articles

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