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X-linked Retinoschisis (XLRS)

What is x-linked retinoschisis?

X-linked retinoschisis (XLRS) is a genetic disorder that is characterized by the loss of vision that cannot be improved with corrective lenses. Its incidence is one in every 10,000. It affects males, as it is an x-linked disorder. 

What are the symptoms of x-linked retinoschisis?

The loss of vision is the major symptom of XLRS. Some affected individuals also experience bleeding in the eye and retinal detachment. 

Some people see a progressive loss of vision starting in childhood, while others experience no progression. Either way, most will reach the point of being legally blind. 

What causes x-linked retinoschisis?

The RS1 gene on the X-chromosome is mutated in those with XLRS. As it is on the X-chromosome, only males can experience the symptoms of this disorder while females can be carriers. 

How is x-linked retinoschisis diagnosed?

This disorder is typically diagnosed during childhood. An eye exam will be conducted, and doctors will also test the function of the retina. If necessary, genetic testing can obtain a diagnosis as well. 

What are the treatments for x-linked retinoschisis?

Treatment is symptomatic. Visual aids may be helpful, and surgery may be required for retinal detachment or bleeding within the eye. 

Where can I find out more about x-linked retinoschisis?

X-Linked Retinoschisis (XLRS) Articles

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