Does Ankylosing Spondylitis Have You Feeling Down? Here’s Why.

Ankylosing spondylitis (AS) patients listen up because we’re talking to y’all!

According to an article published to Medical Xpress, AS patients have lower serotonin levels compared to those without AS. Serotonin is described as the chemical that’s responsible for mood balance, which can control how happy someone may be.

Here are the four big takeaways from their study:

  1. AS patients have serum levels of serotonin that are lower than “healthy” people.
  2. It’s likely that serotonin is an inhibitor of bone formation.
  3. AS patients who receive tumor necrosis factor α (TNF α) have significantly lower serotonin levels than those who don’t recieve treatment.
  4. The differences in serotonin levels have functional impact on osteoblast-like Saos-2 cells. Don’t know what those cells are either? Saos-2 cells are cells that have many osteoblastic features (cells that synthesize the bone) and can be used as a source of bone-related molecules.

Can you relate? Leave a comment below!

Winnie Nash

Winnie Nash

Winnie Nash, born and bred in Charleston, South Carolina, likes to think she’s sweet as tea. Passionate for people, stories, and a little bit of glitter, she has an especially soft spot for patients and their journeys. A writer with true disdain for clichés, Winnie catches every detail of a story—intently listening—craving the next word. Some may call it nosiness, but to her, it’s just wholesome curiosity.

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