Schnitzler syndrome was initially identified in the 1970s.Patients usually have fever, bone and joint pain, fatigue, anemia, enlarged liver and spleen, and a strange rash. The rash is resistant to treatment, and can affect most parts of the body, but it comes and goes. New lesions tend to form, however. Patients rarely go for more than four weeks without the symptomatic rash. The initial medical intervention usually begins at a dermatologist’s practice.
At the Mayo Clinic, researchers noticed that patients weren’t being diagnosed appropriately because Schnitzler syndrome mimics other serious illnesses. The Mayo clinic has a specialized team that can properly diagnose the condition and offer specific therapies for the syndrome.