Acromegaly: Less Fat, but More Diabetes!

I just read an interesting article that explains how individuals with active Acromegaly have less fat and more muscle than those without Acromegaly.

They also have more GH and perhaps IGF-l (a growth factor not unlike insulin). GH and IGF-l actually have several detrimental effects on the body’s insulin processing, making it more insulin resistant.

Do despite being leaner, people with acromegaly are more likely to develop diabetes.

In addition, these excessive secretions lead to atypical fat distribution, with more fat in the trunk and internally, and less even distribution of adipose tissue.


Jessica Gladwell

Jessica Gladwell

Jessica Gladwell is one of PW's consultants and patient editors. She has lived with late-stage, chronic Lyme and POTS since circa 2002. She has also served as a caregiver to close family members with late-stage, chronic Lyme. Before diagnosis, she served as a business consultant for a large corporation and PM for a small digital branding agency. Now, she is proactive in the rare and neurological disease community, spreading awareness and advising on matters of health and lifestyle when living with a chronic illness.

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