Research Links Childhood Strabismus and Mood Disorders

Did you know that there are six muscles attached to each eye which influence the way the eye moves? When these muscles are properly working, the eyes move together and remain aligned. Strabismus, or crossed eyes, occur when problems with the eye muscles, nerves, or area of the brain that directs eye movements cause the eyes to not line up with each other. Learn more about strabismus here

According to Medical Dialogues, new research suggests that strabismus in children is associated with higher rates of mood disorders, such as major depressive disorder (MDD), schizophrenia, and bipolar disorder. However, strabismus was not associated with higher rates of substance abuse issues. Take a look at the full findings published in JAMA Ophthalmology

Researching Strabismus

Typically, researchers have conceptualized strabismus as reducing quality-of-life (QOL). Thus, they wondered if strabismus correlated with the development of mood disorders, which may also inhibit daily function and QOL. Researchers sourced data from 12,005,189 children over an 11-year period. To be included in the study, the children had to be under 19 years old and have a confirmed strabismus diagnosis. Those who did not have strabismus were used as a control group. 

The researchers found that those with strabismus were significantly more likely to have an anxiety disorder. Schizophrenia was the next most likely mood disorder, followed by bipolar disorder and MDD. Additionally, anxiety was more common in those whose eye or eyes turned outward, while bipolar disorder was more common in those whose eye or eyes turned inward.

About Mood Disorders

Major depressive disorder, seasonal affective disorder (SAD), schizophrenia, premenstrual dysphoric disorder (PMDD), and bipolar disorder are all examples of mood disorders. However, it is important to note that these do not encompass the full spread of mood disorders. Mood disorders are psychological states in which emotions do not correlate to one’s experiences and may cause issues with daily life. For example, those with PMDD may experience severe anxiety or depression during pre-menstruation that dissipates during menstruation. Those with bipolar disorder may experience alternating cycles of mania (“highs”) and depression (“lows”). 

A mixture of biological, psychological, environmental, and genetic factors can spur the development of mood disorders. Symptoms also vary depending on each disorder.

Jessica Lynn

Jessica Lynn

Jessica Lynn has an educational background in writing and marketing. She firmly believes in the power of writing in amplifying voices, and looks forward to doing so for the rare disease community.

Share this post

Follow us