A Study of Chronic Fatigue Syndrome and Its Relationship to Enteroviruses

 Frontiers In Medicine recently published a critical review by Maureen Hanson and Adam O’Neal of Cornell University’s Department of Biology and Genetics. The authors searched for the cause of myalgic encephalomyelitis (ME), a term first used in the United Kingdom following an outbreak of an infection in the UK in 1955.

In the U.S., chronic fatigue syndrome (CFS) is more widely used, as the term was initially used by the CDC in 1988. Hence, we refer to the disease as ME/CFS. In reality, both terms describe the same issues.

About ME/CFS

ME/CFS is a multi-system disorder. The cause has not yet been determined although enteroviruses (EVs) have been suspected. EVs are associated with gastrointestinal and respiratory infections of the central nervous system, heart, and muscle. The list of symptoms includes:

  • Fatigue
  • Memory and concentration problems
  • Sore throat
  • Tender lymph nodes
  • Muscle pain
  • Multi-joint pain
  • Headaches
  • Unrefreshing sleep
  • Post-exertional malaise

Researchers point to evidence that they are seeing increased enteroviral infections in ME/CFS patients. However, the results have been inconsistent. Therefore, the last two decades have seen fewer studies related to the disease.

Authors and Evidence

The authors reviewed ME/CFS functional changes related to enterovirus infection. They conducted a critical review of techniques used in previous EV and ME/CFS studies.

The authors came to the conclusion, after submitting a significant amount of evidence, that previous epidemics of ME/CSF did, in fact, result from enterovirus groups. They reiterate that techniques used previously were insufficient to negate enteroviral infections as the cause of ME/CFS. They agree that additional studies, using the most up-to-date molecular techniques, are required.

COVID-19 Steps In

Reports are coming in that people with long-term COVID-19 symptoms are going into remission after they have received anti-SARS COV2 vaccinations. Treating an ME/CFS patient in this manner would not be possible without the presence of the enterovirus. Again, more studies are warranted.

Rose Duesterwald

Rose Duesterwald

Rose became acquainted with Patient Worthy after her husband was diagnosed with Acute Myeloid Leukemia (AML) six years ago. During this period of partial remission, Rose researched investigational drugs to be prepared in the event of a relapse. Her husband died February 12, 2021 with a rare and unexplained occurrence of liver cancer possibly unrelated to AML.

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