Avacopan, a novel oral therapy for antineutrophil cytoplasmic antibody-associated vasculitis (ANCA-AAV), has changed treatment paradigms for this rare but serious disease. However, until now, a validated technique for measuring avacopan…
According to a story from Medscape, a new set of guidelines from the Kidney Disease: Improving Global Outcomes (KDIGO) aims to improve and update standards of care for antineutrophilic cytoplasmic…
Continued From Part One Case #2 The second case involved a sixteen-year-old male in the ICU unit with suspected bacterial hypoxic respiratory failure associated with viral pneumonia. The teen’s history…
A group of autoimmune diseases called anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV) is the subject of a preprint under consideration at Pediatric Rheumatology. ANCA-AAV is characterized by damage to small…
ANCA-associated vasculitis (AAV) generally targets two enzymes, myeloperoxidase (MPO) or proteinase 3 (PR3) located in the granules of monocytes and neutrophils. These enzymes play a critical role in the…
Sometimes, certain drugs may be approved in different countries and not in others. However, drug approval spanning multiple countries highlights the importance of getting drugs and treatments into the hands…
According to a story from ANCA Vasculitis News, the biopharmaceutical company ChemoCentryx has recently made an amendment to its approval application for its investigational therapy. This therapy, called avacopan, is…
According to a story on the Renal Fellow Network, rituximab has emerged in recent years as an effective therapy for ANCA-associated vasculitis (AAV). This is a group of autoimmune diseases…
According to an article in Healio, Dr. Anisha Dua recently addressed attendees at the ACR Clinical Symposium on the subject of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis. Dr. Dua is the…
Welcome to Study of the Week from Patient Worthy. In this segment, we select a study we posted about from the previous week that we think is of particular interest…
According to a story from wndu.com, a fundraiser that was held in Berrien Springs, Michigan, is helping to raise money for Carter Sheline, who recently graduated from high school and…
According to a story from ANCA Vasculitis News, a recent study has determined that monitoring changes in autoantibodies targeting the PR3 protein is useful for predicting ANCA vasculitis remission after…
Recently, the American College of Rheumatology (ACR) virtually held ACR Convergence 2020, the organization's annual meeting. At the meeting, researchers shared new insights in the realm of rheumatology; these were…
In a recent study published in Clinical and Experimental Immunology, researchers determined that patients with high ANCA antibody levels are at an increased risk of having ANCA-associated vasculitis (AAV) relapses. According…
According to a story from GlobeNewswire, Exagen, Inc. recently launched a testing panel called AVISE® Vasculitis AAV, which is designed to help physicians get fast and accurate data for patients…
by Danielle Bradshaw from In The Cloud Copy It has been found that fingolimod - a drug typically used for multiple sclerosis - may also be effective in treating ANCA-associated…
ChemoCentryx has just announced that they have submitted their New Drug Application to the FDA for a novel ANCA-associated vasculitis therapy. It is called avacopan and it's finally something non-steroidal.…
According to a story from ANCA Vasculitis News, a recent review study has determined that patients living with ANCA vasculitis and other related diseases are at a higher than average…
According to a story from Renal & Neurology News, a recent study has found that rituximab is superior to azathioprine therapy in preventing symptoms relapse in patients living with ANCA…
According to a story from Healio, new guidelines for the treatment of different forms of vasculitis recommend the use of biologic therapies as a first-line option for certain patients. It…
According to a story from ANCA Vasculitis News, a recent study has found that a low-dose regimen of glucocorticoids that explicitly exclude the drug methyprednisolone can be a useful therapy…
According to a publication from ANCA Vasculitis News, a recent Spanish study of over 100 individuals diagnosed with ANCA-associated vasculitis found that major infections are a main cause of death…
According to a publication from ANCA Vasculitis News, a new study in International Kidney Reports suggests that stopping treatment of the disease once it goes into remission may lead to…
According to a publication from ANCA Vasculitis News, a sizable number of people who do not have ANCA-associated vasculitis could falsely test positive due to the presence of the associated…
The US Food and Drug Administration (FDA) has approved an Investigational New Drug (IND) application for an experimental drug that is being researched for its use as a treatment for…
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