A Combination of Benmelstobart, Anlotinib, and Chemotherapy Improves Survival Rates in SCLC, Study Suggests
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A Combination of Benmelstobart, Anlotinib, and Chemotherapy Improves Survival Rates in SCLC, Study Suggests

  Advancing patient outcomes hinges on the development of targeted treatments, particularly in conditions with grim prognoses such as small cell lung cancer (SCLC), which typically has a life expectancy…

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Glofitamab with Obinutuzumab Shows Promise in Heavily Pretreated Richter Syndrome

Also known as Richter’s Transformation, Richter syndrome is a rare and aggressive complication of chronic lymphocytic leukemia (CLL). When someone develops Richter syndrome, their CLL can transform into another rare…

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Phase 2b Clinical Study Begins to Evaluate Bexotegrast for IPF
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Phase 2b Clinical Study Begins to Evaluate Bexotegrast for IPF

  The U.S. FDA has approved two treatments for people living with idiopathic pulmonary fibrosis (IPF). These therapies—Esbriet (pirfenidone) and Ofev (nintedanib)—both work to reduce fibrosis, or scarring, in the…

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FDA Clears Global Phase 3 Study of Lisaftoclax for Previously Treated CLL or SLL
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FDA Clears Global Phase 3 Study of Lisaftoclax for Previously Treated CLL or SLL

  In Jordyn Sava's reporting from Targeted Oncology, readers learn that the U.S. Food and Drug Administration (FDA) granted clearance to a global Phase 3 study. This means that the…

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Study Results Available on Dexpramipexole for Eosinophilic Asthma
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Study Results Available on Dexpramipexole for Eosinophilic Asthma

  The Phase 2 EXHALE-1 clinical trial, initiated by clinical-stage biotechnology company Areteia Therapeutics, Inc. ("Areteia"), sought to understand how safe, effective, and well-tolerated dexpramipexole was in reducing symptoms of…

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Do Cross-Over Arms in Clinical Oncology Trials Benefit Patients?
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Do Cross-Over Arms in Clinical Oncology Trials Benefit Patients?

The Cholangiocarcinoma Foundation has recently released a white paper titled “Cross-over arms in oncology clinical trials: An important consideration for patients.” This paper highlights a non-traditional clinical trial approach that…

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CB-010 Shows Promise for B-Cell Non-Hodgkin Lymphoma, Study Shows

Recent results are available from the dose escalation portion of the Phase 1 ANTLER study. In reporting from Targeted Oncology, Jordyn Sava shares that the study included 16 participants living…

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FDA Clears Clinical Study to Evaluate BB-301 for Oculopharyngeal Muscular Dystrophy
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FDA Clears Clinical Study to Evaluate BB-301 for Oculopharyngeal Muscular Dystrophy

  Prior to launching a clinical trial, the FDA must clear an Investigational New Drug (IND) application. This allows the drug to be distributed across state lines, which is important…

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Positive Data Available from Phase 4 Trial for Primary Immunodeficiencies
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Positive Data Available from Phase 4 Trial for Primary Immunodeficiencies

  In a late July 2023 news release, global healthcare company Grifols shared that positive topline data was now available from a Phase 4 clinical study evaluating XEMBIFY (immune globulin…

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Could Melanoma Drugs be Effective in Treating Papillary Craniopharyngioma (PCP)?
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Could Melanoma Drugs be Effective in Treating Papillary Craniopharyngioma (PCP)?

  Each year, there are less than 600 new cases of papillary craniopharyngioma (PCP) diagnosed within the United States. While PCP typically has a good prognosis with treatment, treatment is…

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Positive Topline Data Available on ALTB-268 for Ulcerative Colitis 
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Positive Topline Data Available on ALTB-268 for Ulcerative Colitis 

  In a Phase 1 clinical study, researchers wanted to understand whether ALTB-268, developed by clinical-stage biotechnology company AltruBio Inc., could be effective in treating ulcerative colitis. The study first…

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