AstraZeneca Expands AI-Driven Drug Discovery Efforts in MASH and Cardiomyopathy

As reported on BioSpace, AstraZeneca has entered a major artificial intelligence-focused research collaboration with biotechnology company insitro, committing up to $1.5 billion in potential payments to identify new drug targets…

Continue Reading AstraZeneca Expands AI-Driven Drug Discovery Efforts in MASH and Cardiomyopathy

Bristol Myers Squibb Wins FDA Expansion for Camzyos in Pediatric Obstructive Hypertrophic Cardiomyopathy

As reported on Yahoo! News, Bristol Myers Squibb (BMS) has received an expanded approval from the US Food and Drug Administration (FDA) for Camzyos (mavacamten), extending its use to pediatric…

Continue Reading Bristol Myers Squibb Wins FDA Expansion for Camzyos in Pediatric Obstructive Hypertrophic Cardiomyopathy

Wegovy Linked to Normal Liver Fat Levels in Small Analysis of Adults With Obesity

As reported on Medical Daily, small exploratory analysis suggests that semaglutide, the active ingredient in Wegovy, may substantially reduce liver fat in some adults with obesity. However, the findings come…

Continue Reading Wegovy Linked to Normal Liver Fat Levels in Small Analysis of Adults With Obesity

Phase 3 IMAgINATION Trial of Sefaxersen Meets Primary Endpoint in IgA Nephropathy

Investigational once-monthly therapy significantly reduced proteinuria versus placebo at 37 weeks, according to interim findings from the phase 3 study. As reported on PharmaBiz, Roche has reported positive interim findings…

Continue Reading Phase 3 IMAgINATION Trial of Sefaxersen Meets Primary Endpoint in IgA Nephropathy

FDA Grants Priority Review to Imfinzi-Enfortumab Vedotin Regimen for Muscle-Invasive Bladder Cancer

As reported on PharmaBiz, the FDA has accepted AstraZeneca’s supplemental Biologics License Application for durvalumab plus neoadjuvant enfortumab vedotin in patients with muscle-invasive bladder cancer who cannot receive or have…

Continue Reading FDA Grants Priority Review to Imfinzi-Enfortumab Vedotin Regimen for Muscle-Invasive Bladder Cancer

Singapore Approves Wegovy for MASH With Moderate to Advanced Liver Fibrosis

Semaglutide 2.4 mg becomes Singapore’s first approved therapy for adults with noncirrhotic metabolic dysfunction-associated steatohepatitis and F2-F3 fibrosis. As reported on the Manila Times, Singapore’s Health Sciences Authority (HSA) has…

Continue Reading Singapore Approves Wegovy for MASH With Moderate to Advanced Liver Fibrosis

Organoid Advances Could Open New Paths for Spinal Cord and Peripheral Nerve Repair

As reported on News Medical, researchers are increasingly exploring laboratory-grown organoids as potential tools for repairing damage caused by spinal cord and peripheral nerve injuries. A review published in Engineering…

Continue Reading Organoid Advances Could Open New Paths for Spinal Cord and Peripheral Nerve Repair

FDA Greenlights Acepodia’s Investigational ADC Candidate ACE723 for Advanced Liver Cancer Trial

As reported on PharmaBiz, the US Food and Drug Administration (FDA) has authorized Acepodia to proceed with clinical testing of ACE723, an investigational antibody-drug conjugate (ADC) designed for patients with…

Continue Reading FDA Greenlights Acepodia’s Investigational ADC Candidate ACE723 for Advanced Liver Cancer Trial

Roche-Partnered B7-H3 ADC Meets Phase 3 Endpoint in Small Cell Lung Cancer, Shows Competitive Safety Profile

As reported on Fierce BioTech, a phase 3 study conducted by MediLink has delivered positive results for Roche-partnered antibody-drug conjugate (ADC) tambotatug pelitecan (tam-peli), also known as YL201, in patients…

Continue Reading Roche-Partnered B7-H3 ADC Meets Phase 3 Endpoint in Small Cell Lung Cancer, Shows Competitive Safety Profile

Imfinzi–Imdelltra Combination Extends Survival in First-Line Extensive-Stage Small Cell Lung Cancer

As reported on PharmaBiz, a combination of Imfinzi (durvalumab) and Imdelltra (tarlatamab) has delivered significant improvements in survival outcomes for patients with extensive-stage small cell lung cancer (ES-SCLC), according to…

Continue Reading Imfinzi–Imdelltra Combination Extends Survival in First-Line Extensive-Stage Small Cell Lung Cancer

FDA Authorizes Daraxonrasib for Metastatic Pancreatic Cancer After Positive Phase 3 Trial Results

As reported on World Pharma News, the U.S. Food and Drug Administration has granted approval to daraxonrasib, an oral RAS-targeting therapy, for adults with metastatic pancreatic adenocarcinoma who have previously…

Continue Reading FDA Authorizes Daraxonrasib for Metastatic Pancreatic Cancer After Positive Phase 3 Trial Results

Guardant360 CDx Approved as Companion Diagnostic for AstraZeneca’s Etcamah in ESR1-Mutated Breast Cancer

As reported on Fierce BioTech, Guardant Health has secured U.S. Food and Drug Administration approval for its Guardant360 CDx liquid biopsy test as the companion diagnostic for AstraZeneca’s newly approved…

Continue Reading Guardant360 CDx Approved as Companion Diagnostic for AstraZeneca’s Etcamah in ESR1-Mutated Breast Cancer