Pemvidutide Shows Sustained Weight Loss and Liver Improvement in Extended MASH Trial Data

Altimmune has released updated 48-week results from its phase 2 trial of pemvidutide, a GLP-1/glucagon dual receptor agonist being developed for metabolic dysfunction-associated steatohepatitis (MASH), demonstrating continued weight loss and…

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CRISPR Therapeutics Shares Promising Updates on Zugo-cel in Autoimmune and Oncology Trials

CRISPR Therapeutics has announced encouraging early results for zugocaptagene geleucel (zugo-cel), its investigational allogeneic CAR T therapy targeting CD19, in both autoimmune diseases and hematologic malignancies. Autoimmune Disease Progress In…

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Coya Therapeutics Advances Novel Immunotherapy into Clinical Development for Frontotemporal Dementia

Coya Therapeutics has achieved an important regulatory milestone with U.S. FDA acceptance of an Investigational New Drug (IND) application for COYA 302, marking the advancement of a promising new treatment…

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Deucrictibant Provides Rapid Relief for Hereditary Angioedema Attack Symptoms

A new oral medication has demonstrated remarkable effectiveness in treating hereditary angioedema (HAE) attacks, offering patients significantly faster symptom relief compared to existing options. According to Healio.com, the RAPIDe-3 study…

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Incyte Reports Positive Phase III Results for Tafasitamab in First-Line DLBCL Treatment

Incyte has announced encouraging top-line findings from its pivotal Phase III frontMIND trial, evaluating tafasitamab (marketed as Monjuvi/Minjuvi) in combination with lenalidomide and the standard R-CHOP regimen for newly diagnosed…

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FDA Approve Drug That Targets Root Cause of Life-Threatening Kidney Disease Affecting Children and Young Adults 

Iowa University researchers at its Children’s Hospital led the effort that found a new target.  According to the Iowa Carver College of Medicine, to date, efforts by researchers focused on…

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Tonsillectomy Plus Immunosuppression Improves Outcomes in High-Risk IgA Nephropathy Among Caucasians

Editor's Note: The following study results were first published in Nephrology Dialysis Transplantation (December 16, 2025) and later shared in the Oxford Academic. The original study authors are Zinaida S.…

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Breaking Into a Crowded Market: Otsuka’s Pioneering APRIL Inhibitor Marks New Era in Kidney Disease Treatment

Otsuka has claimed a significant victory in the increasingly competitive immunoglobulin A nephropathy (IgAN) field with FDA accelerated approval of Voyxact, the first-in-class anti-APRIL biologic therapy designed to treat this…

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FDA Approves J&J’s Akeega for BRCA2-Mutated mCSPC, Marking a New Era in Precision Prostate Cancer Care

As reported on FiercePharma, Johnson & Johnson has secured a significant milestone in prostate cancer treatment with the FDA’s approval of Akeega for patients with BRCA2-mutated metastatic castration-sensitive prostate cancer…

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When AI Sees What Radiologists Miss: How Artificial Intelligence is Reshaping Breast Cancer Detection

A groundbreaking study from Massachusetts General Hospital reveals that artificial intelligence is catching breast cancers that skilled radiologists initially overlook. As reported by Business Wire, Hologic's Genius AI Detection solution…

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GENESIS Pharma Secures Exclusive Rights to Donidalorsen for Hereditary Angioedema in CEE

As reported on PharmaBiz, GENESIS Pharma has announced an exclusive agreement with Otsuka Pharmaceutical Europe Ltd. (OPEL) to distribute and commercialize donidalorsen across 14 Central and Eastern European countries, including…

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Renalys Pharma Announces Positive Phase III Results for Sparsentan in Japanese IgA Nephropathy Patients

As reported on PharmaBiz, Renalys Pharma has reported encouraging topline data from its Phase III trial evaluating sparsentan (RE-021), an oral dual endothelin and angiotensin II receptor antagonist, in Japanese…

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