Breaking New Ground: FDA Approves First Gene Therapy to Address the Root Cause of GSDIa

Historic Milestone Offers Relief from Relentless Burden of Glycogen Storage Disease Type Ia According to a recent press release from Ultragenyx, after decades of medical innovation and tireless advocacy from…

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TransThera Secures China’s First Approval for Patients With FGFR Inhibitor-Resistant Cholangiocarcinoma

As reported by allsci, China’s National Medical Products Administration (NMPA) has granted conditional approval to TransThera Sciences’ Yochanra (tinengotinib) for adults with unresectable, advanced, or metastatic cholangiocarcinoma (CCA) carrying FGFR2…

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Zydus Introduces India’s First Once-Daily Nebulized LAMA for COPD Maintenance

As reported by PharmaBiz, Zydus Lifesciences has announced the launch of Revahale (revefenacin), a once-daily nebulized long-acting muscarinic antagonist (LAMA) for the maintenance treatment of chronic obstructive pulmonary disease (COPD).…

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AstraZeneca Ends Phase 3 Volrustomig Study in Lung Cancer After Interim Review Signals Low Likelihood of Success

As reported on BioSpace, AstraZeneca has discontinued a pivotal Phase 3 trial evaluating its investigational bispecific antibody volrustomig in advanced non-small cell lung cancer (NSCLC) after an interim analysis indicated…

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Tirzepatide May Enhance Biologic Therapy Outcomes in Psoriatic Arthritis Patients With Obesity

New observational research suggests that addressing obesity alongside inflammatory joint disease could improve treatment outcomes for people with psoriatic arthritis (PsA). As reported on MedIndia, a recent propensity score-matched analysis…

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Impending PPAR-Targeted Therapies Expand Treatment Possibilities for Primary Biliary Cholangitis

As reported on News Medical, researchers are highlighting a new class of therapies that could improve outcomes for people living with primary biliary cholangitis (PBC), a chronic autoimmune liver disease…

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LEVI-04 Shows Promise as a Novel Non-Opioid Therapy for Knee Osteoarthritis in Phase 2 Trial

A recent study shared by The Lancet shows that a first-in-class investigational therapy targeting neurotrophin-3 (NT-3) significantly reduced pain and improved function in patients with knee osteoarthritis (OA), according to…

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Treating Inflammation vs. Bacteria

According to recent reports, assistant pediatric professor at the Boston Children’s Hospital, Prof. Meenakshi Rao, noted that infections associated with Clostridioides difficile (C. Diff.) are difficult to eradicate. Nonetheless, once the infection is under…

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Otsuka Reports Two-Year Kidney Function Benefit With Sibeprenlimab in Phase 3 IgA Nephropathy Trial

Sibeprenlimab-szsi (VOYXACT) slowed estimated glomerular filtration rate decline versus placebo over 24 months in adult patients with primary IgA nephropathy, according to Phase 3 VISIONARY results announced by Otsuka. Otsuka…

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