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Orphan Drug Designation Granted to Three Active Moieties of INT230-6 for Soft Tissue Sarcoma (STS)

• Post author:Jessica Lynn
• Post published:September 7, 2023
• Post category:Soft Tissue Sarcoma

INT230-6, developed by clinical-stage biotechnology company Intensity Therapeutics (“Intensity”), is an investigational therapy comprising three moieties: cisplatin, SHAO-FA (a penetration enhancing molecule), and vinblastine sulfate. A moiety, in this sense,…

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Rare Community Profiles: Their Daughter’s Rare Disease Empowered the Traller Family to Advocate for ASPS Awareness and Research

• Post author:Jessica Lynn
• Post published:April 12, 2023
• Post category:Alveolar soft part sarcoma/Sarcoma/Soft Tissue Sarcoma

Rare Community Profiles     Rare Community Profiles is a new Patient Worthy article series of long-form interviews featuring various stakeholders in the rare disease community, such as patients, their…

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Veyonda for STS Granted Orphan Drug Designation

• Post author:Jessica Lynn
• Post published:April 15, 2022
• Post category:Soft Tissue Sarcoma

In the United States, Orphan Drug designation is granted by the FDA to drugs or biologics intended to treat, prevent, or diagnose rare diseases or conditions. “Rare” is defined as…

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When A Survivor’s Compassion Turns to Guilt

• Post author:Rose Duesterwald
• Post published:December 21, 2021
• Post category:Soft Tissue Sarcoma

Geraldine is Senior Vice President of TheGrio’s, known as Black America’s News. Although she never met Virgil Abloh, she followed his career and knew of his many talents. Geraldine says…

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IMX-110 for Soft Tissue Sarcoma Earns Orphan Drug Designation

• Post author:Jessica Lynn
• Post published:October 7, 2021
• Post category:Soft Tissue Sarcoma

  To best address the needs of patients with rare diseases and rare cancers, additional treatment options are necessary. But developing these treatment options can be time-consuming and sometimes difficult.…

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Sotigalimab for STS Earns Orphan Drug Status

• Post author:Jessica Lynn
• Post published:August 9, 2021
• Post category:Soft Tissue Sarcoma

Orphan drug designation is granted in the United States to expedite the development and review of drugs and biologics intended to treat patients with rare conditions (over 200,000 Americans). Once…

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New ASTRO Clinical Guideline Shares Insights on Radiation for STS

• Post author:Jessica Lynn
• Post published:August 3, 2021
• Post category:Soft Tissue Sarcoma

  Clinical guidelines are often used to improve patient treatment. These guidelines use evidence reviews, as well as an examination of other standards-of-care, to optimize patient care and outcomes. According…

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Envafolimab for Soft Tissue Sarcoma Granted Orphan Drug Status

• Post author:Jessica Lynn
• Post published:June 29, 2021
• Post category:Soft Tissue Sarcoma

An Orphan Drug designation is granted to drugs or biologics intended to treat patients with rare diseases or conditions, affecting less than 200,000 Americans. Because it can sometimes be difficult…

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Annamycin for STS Lung Metastases Granted Fast Track Designation

• Post author:Jessica Lynn
• Post published:April 15, 2021
• Post category:Soft Tissue Sarcoma

In late March 2021, the FDA gave Fast Track designation to annamycin. The treatment, initially developed for patients with acute myeloid leukemia (AML), is now being explored for patients with…

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Sarcoma Patients Need Specialized Expert Care

• Post author:Trudy Horsting
• Post published:March 4, 2021
• Post category:Soft Tissue Sarcoma

Sarcoma Sarcoma is a cancer that accounts for 1% of all adult cancers. It can affect individuals of any age and can impact any part of the body. It grows…

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Polish Agency Awarded Grant for Annamycin Clinical Trial for STS

• Post author:Jessica Lynn
• Post published:February 15, 2021
• Post category:Rhabdomyosarcoma- embryonal/Soft Tissue Sarcoma

In a recent press release, pharmaceutical company Moleculin Biotech, Inc. ("Moleculin") shared a recent advance in the sphere of medical and health research. Agencja Badań Medycznych, a Polish agency which contributes…

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Next Generational Sequencing: Imaging Non-GIST Sarcoma Tumors

• Post author:Rose Duesterwald
• Post published:April 29, 2020
• Post category:Rare Disease/Soft Tissue Sarcoma

  An earlier online article in JCO Precision Oncology presents a study of next-generation sequencing (NGS) as it applies to molecular profiling of non-gastrointestinal stromal (GIST) soft tissue sarcomas .…

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Study Tests Combination Treatment for Advanced Soft Tissue Sarcoma

• Post author:James Moore
• Post published:March 17, 2020
• Post category:Rare Disease/Soft Tissue Sarcoma

According to a story from Hindawi, a recent study tested a combination treatment for patients with metastatic or locally advanced soft tissue sarcoma. Outcomes for these patients are poor if…

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British Science Journal Authors Voice Concerns Over Low Standards Supporting Cancer Drugs

• Post author:Rose Duesterwald
• Post published:September 24, 2019
• Post category:Cancer/Multiple Myeloma/Soft Tissue Sarcoma

  Fierce Biotech recently focused on a report by The BMJ, a British science journal, on the validity of clinical trials which are critical to decision making by patients and…

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Birth of Healthy Baby Monkey Indicates Promise of New Technique To Preserve Fertility of Childhood Cancer Patients

• Post author:Trudy Horsting
• Post published:March 29, 2019
• Post category:Brain Cancer/Soft Tissue Sarcoma/Testicular Cancer

As the field of medicine has continually advanced, more and more children (now approximately 80%) are surviving cancer diagnoses. It's amazing. It also means that researchers are able to focus…

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Cancer Drug LARTRUVO Fails to Meet Primary Endpoint in Soft Tissue Sarcoma Clinical Trial

• Post author:James Moore
• Post published:January 24, 2019
• Post category:Soft Tissue Sarcoma

According to a story from PR Newswire, the international drug developer Eli Lilly and Company recently announced the results of a Phase 3 clinical trial testing the company's drug LARTRUVO…

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Recently Approved US Drug Helps Canadian Boy With Thyroid Cancer

• Post author:James Moore
• Post published:December 18, 2018
• Post category:Soft Tissue Sarcoma/Thyroid Cancer

According to a story from Global Knock, nine year old Ashton Leeds has been living an active life again lately, but a year ago, things were not looking up for…

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Second Ever Cancer Treatment Based on Biomarkers Approved by FDA

• Post author:Trudy Horsting
• Post published:November 29, 2018
• Post category:Rare Disease/Salivary gland cancer- adult/Soft Tissue Sarcoma/Thyroid Cancer

On November 26, 2018, a new drug was given accelerated approval by the FDA. Not only that, but it was granted orphan drug designation and breakthrough therapy designation. The drug…

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Shaving Heads, Raising Money, Beating Cancer

• Post author:Trudy Horsting
• Post published:October 9, 2018
• Post category:Soft Tissue Sarcoma

Lisa Clayton has been diagnosed with cancer as many times as she's given birth. She's a mom of 5, and she has just heard the news "you have cancer" for…

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5-Year-Old with Rhabdomyosarcoma Creates Obituary in His Own Words

• Post author:Athena Lee
• Post published:August 22, 2018
• Post category:Rhabdomyosarcoma- embryonal/Soft Tissue Sarcoma

According to a story reported by the New York Times, 5-year-old Garrett Matthias had already thought about what he wanted his funeral to be like. He didn't want it to…

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Planting the Seeds of Sarcoma Awareness

• Post author:James Moore
• Post published:August 20, 2018
• Post category:Rare Disease/Soft Tissue Sarcoma

According to a story from Deseret News, sarcoma patients at the Huntsman Cancer Institute are planting sunflowers as a way to spread awareness about sarcoma, a rare and aggressive form…

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A Woman Diagnosed With Soft Part Sarcoma Received Treatment With the Help of Miracle Flights

• Post author:Anna Hewitt
• Post published:July 10, 2018
• Post category:Soft Tissue Sarcoma

Miracle Flights help children to fly to access medical treatment. They work to support people like Shelby, who was diagnosed with alveolar soft part sarcoma at the age of seventeen.…

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Man With Soft Tissue Sarcoma is Refusing to Let His Diagnosis Spoil His Recent Marriage

• Post author:James Moore
• Post published:May 3, 2018
• Post category:Rare Disease/Soft Tissue Sarcoma

According to a story from the Peterborough Telegraph, James Willis received a disaster diagnosis on his first Valentine's Day after getting married at age 29. James had been worried about…

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How Dogs Are Paving the Way in Cancer Research

• Post author:Patient Worthy Contributor
• Post published:November 3, 2017
• Post category:Rare Disease/Soft Tissue Sarcoma

Dogs, with their pure hearts and boundless supply of affection, have made life better for humans for a long time. Dogs aren't just making people feel better by giving them…

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Huge Childhood Cancer Study Now Underway

• Post author:Sarah Lau
• Post published:August 8, 2017
• Post category:Mantle Cell Lymphoma/Marginal Zone Lymphoma/Neuroblastoma/Rare Disease/Soft Tissue Sarcoma

The Children’s Oncology Group (COG) and the National Cancer Institute (NCI) and have begun collaborating on a new project, to be known as the Pediatric Molecular Analysis for Therapy Choice…

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