Study Finds Systemic Mastocytosis Patients Without CMIHR History Don’t Need Premedication Prior to Imaging
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Study Finds Systemic Mastocytosis Patients Without CMIHR History Don’t Need Premedication Prior to Imaging

Results from a study on systemic mastocytosis (SM) have recently been published. This investigation aimed to understand the prevalence of contrast media induced hypersensitivity reactions (CMIHR) in different subtypes of…

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Investigative Therapy to Treat Underlying Cause of Systemic Mastocytosis is Under FDA Review

Blueprint Medicines Corporation has just announced that they have submitted a supplemental New Drug Application (NDA) to the FDA. This application is for a therapy called AYVAKIT, which was developed…

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Positive Data Announced from AYVAKIT Clinical Trials for Systemic Mastocytosis
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Positive Data Announced from AYVAKIT Clinical Trials for Systemic Mastocytosis

  In a recent press release, precision therapy company Blueprint Medicines Corporation announced positive results from two clinical trials: EXPLORER and PATHFINDER. The trials examined the safety, efficacy, and tolerability…

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The Latest Advances in Systemic Mastocystosis Molecular Biology Could Change Future Treatment
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The Latest Advances in Systemic Mastocystosis Molecular Biology Could Change Future Treatment

By Lauren Thayer from In The Cloud Copy Systemic mastocytosis (SM) is a complicated condition of the blood in which excessive numbers of mast cells (a type of white blood…

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Data From a Phase I Study of a Drug to Treat Systemic Mastocytosis Has Been Released
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Data From a Phase I Study of a Drug to Treat Systemic Mastocytosis Has Been Released

Promising data from the ongoing Phase I clinical trial Explorer has been announced by Blueprint Medicines Corporation. The trial is designed to evaluate the effects of the experimental drug avapritinib…

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