Phase 3 Data Available on Pevonedistat for AML, MDS, CMML
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Phase 3 Data Available on Pevonedistat for AML, MDS, CMML

In the Phase 3 PANTHER clinical trial, also known as the Pevonedistat-3001 study, researchers were evaluating pevonedistat in conjunction with azacitidine for patients with acute myeloid leukemia (AML), myelodysplastic syndromes…

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FDA Halted Phase 3 Trial for Cerebral Adrenoleukodystrophy Due to Participant Developing MDS
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FDA Halted Phase 3 Trial for Cerebral Adrenoleukodystrophy Due to Participant Developing MDS

      Science Magazine recently joined other news sources in reporting that Bluebird Bio’s Phase 3 clinical trial investigating a treatment for a neurological disease was put on hold by…

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The MDS Foundation’s Outcomes for High-Risk MDS Patients Undergoing Transplant vs. Standard Non-Transplant Therapies Webinar

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Outcomes for High-Risk MDS Patients Undergoing Transplant vs. Standard Non-Transplant Therapies August 7, 2021 Speaker: Erica D. Warlick, MD, University of Minnesota Medical Center This free webinar provides an overview…

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Venclexta with Azacitidine Granted Breakthrough Therapy Designation for MDS
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Venclexta with Azacitidine Granted Breakthrough Therapy Designation for MDS

In a news release from July 21, 2021, biotechnology company Genentech shared that its therapy Venclexta (venetoclax), in conjunction with azacitidine, received Breakthrough Therapy designation from the FDA. Overall, the…

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The MDS Foundation’s Webcast de MDS en Español

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Que son los sindromes mielodisplasicos? Guillermo Montalbán Bravo, MD, MD Anderson Cancer Center Este seminario les va a proveer como se determina el diagnóstico de MDS, se estará enfocando en…

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The MDS Foundation’s Clinical Implications of Genetic Mutations in Myelodysplastic Syndromes Webinar

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Clinical Implications of Genetic Mutations in Myelodysplastic Syndromes April 17, 2021 Speaker: Rami Komrokji, MD; Moffitt Cancer Center Join this webinar to learn the latest about the genetics of myelodysplastic syndromes.…

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First Patient Dosed in CA-4948 Trial for Hematologic Malignancies
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First Patient Dosed in CA-4948 Trial for Hematologic Malignancies

The first patient has been dosed in a Phase 1 clinical trial, which is exploring Curis Inc.'s CA-4948 in conjunction with ibrutinib for hematologic malignancies. Examples of hematologic malignancies include…

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Risk of Myelodysplastic Syndrome and Acute Myeloid Leukemia May Increase with PARP Inhibitors
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Risk of Myelodysplastic Syndrome and Acute Myeloid Leukemia May Increase with PARP Inhibitors

Poly (ADP-Ribose) polymerase inhibitors (PARP inhibitors) are used to treat neoplasms. They are frequently used as a therapy for ovarian cancer. A recent study has attempted to detect the possibility…

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Experimental Treatment Could be Useful in Numerous Rare and Deadly Cancers
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Experimental Treatment Could be Useful in Numerous Rare and Deadly Cancers

While novel treatments have been rapidly emerging onto the drug scene, new treatment options for pancreatic cancer have fallen behind. But now, according to OncLive’s interview with Dr. P.A. Philip,…

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50% Enrollment Reached in Imetelstat Trial for MDS
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50% Enrollment Reached in Imetelstat Trial for MDS

Since its conception, biopharmaceutical company Geron Corporation ("Geron") has worked to develop first-in-class therapies for hematologic myeloid malignancies. More recently, Geron began evaluating imetelstat for patients with lower risk myelodysplastic syndromes…

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Myelodysplastic Syndromes: Gene Expression Could Predict Azacitidine Response
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Myelodysplastic Syndromes: Gene Expression Could Predict Azacitidine Response

According to a story from Hematology Advisor, a recent study released in Scientific Reports indicates that gene expression has the potential to predict both primary resistance and treatment response in patients living…

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UT Southwestern Expands Diagnostic and Treatment Approaches for Aplastic Anemia, MDS
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UT Southwestern Expands Diagnostic and Treatment Approaches for Aplastic Anemia, MDS

What are the best treatments and diagnostic approaches for blood disorders like aplastic anemia and myelodysplastic syndromes (MDS)? The UT Southwestern Medical Center is trying to streamline these options and…

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