The FDA Approves An Expanded Chemotherapy Treatment For Acute Myeloid Leukemia to Include Children
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The FDA Approves An Expanded Chemotherapy Treatment For Acute Myeloid Leukemia to Include Children

  Cancer Network recently reported that Jazz Pharmaceuticals’ Vyxeos was approved by the FDA to treat therapy-related pediatric patients one year or older who were newly diagnosed with acute myeloid…

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First Patient Dosed in CA-4948 Trial for Hematologic Malignancies
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First Patient Dosed in CA-4948 Trial for Hematologic Malignancies

The first patient has been dosed in a Phase 1 clinical trial, which is exploring Curis Inc.'s CA-4948 in conjunction with ibrutinib for hematologic malignancies. Examples of hematologic malignancies include…

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NMPA Grants Conditional Approval to XOSPATA for FLT3mut+ AML
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NMPA Grants Conditional Approval to XOSPATA for FLT3mut+ AML

  In an early February press release, pharmaceutical company Astellas Pharma Inc. ("Astellas") shared that XOSPATA (gilteritinib) was given conditional approval in China for the treatment of patients with FLT3-mutated…

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Risk of Myelodysplastic Syndrome and Acute Myeloid Leukemia May Increase with PARP Inhibitors
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Risk of Myelodysplastic Syndrome and Acute Myeloid Leukemia May Increase with PARP Inhibitors

Poly (ADP-Ribose) polymerase inhibitors (PARP inhibitors) are used to treat neoplasms. They are frequently used as a therapy for ovarian cancer. A recent study has attempted to detect the possibility…

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Sabatolimab Can Be Added Safely to Hypomethylating Agents in the Treatment of MDS and AML

Dr. Andrew Brunner, an oncologist at Massachusetts Cancer Center was recently interviewed by Targeted Oncology. The discussion centered around a phase 1b clinical trial (NCT03066648) investigating sabatolimab together with hypomethylating…

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Experimental Treatment Could be Useful in Numerous Rare and Deadly Cancers
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Experimental Treatment Could be Useful in Numerous Rare and Deadly Cancers

While novel treatments have been rapidly emerging onto the drug scene, new treatment options for pancreatic cancer have fallen behind. But now, according to OncLive’s interview with Dr. P.A. Philip,…

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Phase 1b Data Shows Magrolimab Clinical Response for AML
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Phase 1b Data Shows Magrolimab Clinical Response for AML

In early December 2020, biopharmaceutical company Gilead Sciences, Inc. ("Gilead") shared updated results from a Phase 1b clinical trial evaluating magrolimab for patients with treatment-naïve acute myeloid leukemia (AML). Generally,…

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A New Treatment for BPDCN is on Track for EU Approval
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A New Treatment for BPDCN is on Track for EU Approval

According to a story from PR Newswire, the pharmaceutical and diagnostics company The Menarini Group recently announced that its drug tagraxofsup (marketed as Elzonris) has a received a positive opinion…

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Astellas Pharma Provides Help, Guidance, and Hope for Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML)
Andrew Krivoshik, M.D., Ph.D., was promoted to senior vice president and Oncology Therapeutic Area Head on April 1, 2019

Astellas Pharma Provides Help, Guidance, and Hope for Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML)

Astellas Pharma, headquartered in Northbrook, Illinois presents its Be R/Ready program to promote patient-physician communication as well as other valuable and informative resources. Their program centers around patients with relapsed…

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A New Investigative Treatment Option for Acute Myeloid Leukemia Produces Positive Results
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A New Investigative Treatment Option for Acute Myeloid Leukemia Produces Positive Results

A new study has uncovered that using a hypomethylating agent in combination with a BCL2 inhibitor called Venetoclax may be advantageous as a therapeutic option for individuals with acute myeloid…

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Experimental Therapies for Small Cell Lung Cancer and Acute Myeloid Leukemia Earn Orphan Drug Designation
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Experimental Therapies for Small Cell Lung Cancer and Acute Myeloid Leukemia Earn Orphan Drug Designation

According to a story from BioSpace, the biotechnology company Ascentage Pharma announced that two of its investigational treatments have recently received Orphan Drug designation from the US Food and Drug…

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The First Patient has Been Dosed with an Investigative Therapy for Acute Myeloid Leukemia

Immune-One Therapeutics has just announced that they have dosed their first acute myeloid leukemia (AML) patient in their Phase 1 trial investigating IO-202. This therapy is an immune inhibitory receptor that works…

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2 TP53 Mutations Worsen Blood Cancer Severity, Says Study
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2 TP53 Mutations Worsen Blood Cancer Severity, Says Study

Recently, the MDS Foundation announced that two TP53 gene mutations result in worse patient outcomes in myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). According to their international and multi center study,…

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Onureg Approved for Continuous AML Treatment
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Onureg Approved for Continuous AML Treatment

Earlier this week, the FDA approved oral azacitidine (Onureg) for patients with acute myeloid leukemia (AML). According to the ASCO Post, Onureg continuously treats adult patients who previously achieved remission.…

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