Eftilagimod Alfa Setback: Immutep Halts Landmark Lung Cancer Trial Following Futility Analysis

Immutep Limited has announced the discontinuation of TACTI-004, a pivotal Phase III clinical trial investigating eftilagimod alfa (efti) as a first-line treatment for advanced non-small cell lung cancer (NSCLC). According…

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ImmunityBio Reports Encouraging Evidence That ANKTIVA Enhances Immune Recovery in NSCLC When Paired With Checkpoint Inhibitors

As reported on Business Wire, ImmunityBio has released new clinical findings suggesting that its interleukin‑15 superagonist, ANKTIVA® (nogapendekin alfa inbakicept), may help restore immune function and improve survival outcomes in…

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AstraZeneca’s LATIFY Trial Misses Primary Endpoint in Previously Treated Advanced NSCLC

As reported on PharmaBiz, AstraZeneca’s phase III LATIFY trial has fallen short of its primary objective, with the combination of the ATR inhibitor ceralasertib and the PD‑L1 inhibitor Imfinzi (durvalumab)…

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ICYMI: Alecensa Exhibited Unprecedented Results for Patients with Early-Stage Lung Cancer
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ICYMI: Alecensa Exhibited Unprecedented Results for Patients with Early-Stage Lung Cancer

Over 50% of non-small cell lung cancer patients (NSCLC) will experience a recurrence after surgery. The cancer recurs even after adjuvant chemotherapy after major surgery. ALINA’s data show that Alecensa…

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Non-small Cell Lung Cancer: Alecensa Achieved Disease-Free Survival in Phase III Interim Analysis
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Non-small Cell Lung Cancer: Alecensa Achieved Disease-Free Survival in Phase III Interim Analysis

   Currently, almost half the patients with non-small cell lung cancer (NSCLC) will see their disease return despite aggressive chemotherapy treatment (adjuvant surgery). Adjuvant therapy is treatment that is given…

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Different ALK inhibitors Lead to Different Outcomes in ALK-Positive Non-Small Cell Lung Cancer
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Different ALK inhibitors Lead to Different Outcomes in ALK-Positive Non-Small Cell Lung Cancer

Dr. Joshua Sabari, a professor at New York University's Department of Medicine, has recently spoken about the different treatment options for ALK-positive non-small cell lung cancer (NSCLC). Specifically, he discussed…

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FoundationOne CDx is Now FDA Approved as a Diagnostic Tool For ALK+ Non-Small Cell Lung Cancer
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FoundationOne CDx is Now FDA Approved as a Diagnostic Tool For ALK+ Non-Small Cell Lung Cancer

FoundationOne CDx is a comprehensive genomic profiling test that is tissue based. It is used to identify individuals diagnosed with ALK+ non-small-cell lung cancer (NSCLC) who will be eligible for…

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Daiichi Sankyo and AstraZeneca Partner to Evaluate Therapy for EGFR-Mutated NSCLC
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Daiichi Sankyo and AstraZeneca Partner to Evaluate Therapy for EGFR-Mutated NSCLC

  Recently, Daiichi Sankyo and AstraZeneca announced a clinical trial collaboration to determine whether using a combination of TAGRISSO (osimertinib) and patritumab deruxtecan (U3-1402) would be effective in treating patients…

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