A Molecular Signature on Stressed Liver Cells Provides PSC Patients With A New Clue to Their Condition
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A Molecular Signature on Stressed Liver Cells Provides PSC Patients With A New Clue to Their Condition

The rare liver disease primary sclerosing cholangitis (PSC) may impact just .01% of people, but the extremely pernicious disorder's attacks on the liver mean bearers of the disorder account for…

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Organs-On- A-Chip: A Novel Approach to Studying Inflammatory Bowel Disease

Biological engineers at MIT are using a new technique to study various organs and their interaction with our immune system. According to a recent article in Science Daily, the researchers…

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New Center for Research of Primary Sclerosing Cholangitis Created in Boston
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New Center for Research of Primary Sclerosing Cholangitis Created in Boston

Copyscape score: 2% Brigham and Women's is launching the nation's first ever center to conduct research on primary sclerosing cholangitis, a rare liver disease that affects about 30,000 people in…

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Primary Sclerosing Cholangitis: This Invention Can Allow Donor Livers to Stay “Alive” Longer Before Transplant
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Primary Sclerosing Cholangitis: This Invention Can Allow Donor Livers to Stay “Alive” Longer Before Transplant

According to a story from mirror.co.uk, a new invention called OrganOx has the potential to make liver transplants more effective and more widely available in the UK. A liver transplant…

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Proof of Concept Study of Investigative Primary Sclerosing Cholangitis Drug Begins
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Proof of Concept Study of Investigative Primary Sclerosing Cholangitis Drug Begins

According to a press release from the German-American biotechnology company Immunic Therapeutics, the Company recently began a proof-of-concept trial for its investigational primary sclerosing cholangitis treatment, IMU-838. About Primary Sclerosing…

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First Patient Enrolls for Primary Sclerosing Cholangitis Proof-of-Concept Study
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First Patient Enrolls for Primary Sclerosing Cholangitis Proof-of-Concept Study

According to a story from BioSpace, the biopharmaceutical company Immunic, Inc. has announced that the first patient has signed up for its proof-of-concept clinical study. This study is intended to…

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Mouse Model Continues to Show Efficacy of GKT831 for Treating Cholestatic Fibrosis in Primary Biliary Cholangitis

Preclinical data supporting the efficacy of GKT831 as a potential therapy for cholestatic fibrosis has just been published in the Journal of Hepatology. GKT831 GKT831 is both a NOX1 enzyme and…

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Phase 2a Clinical Trial for Investigational Cell Therapy Now Recruiting Primary Sclerosing Cholangitis and Autoimmune Hepatitis Patients

Primary Sclerosing Cholangitis (PSC) and Autoimmune Hepatitis (AIH) are both rare and chronic liver diseases. They cause the bile ducts in the liver to become inflamed, resulting in severe liver damage.…

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Immunotherapy Drug to be Tested for Autoimmune Hepatitis and Primary Sclerosing Cholangitis

According to a story from finanzen.at, the biotechnology company Orbsen Therapeutics recently announced that its immunotherapy product ORBCEL-C is to be tested in a multi-site clinical trial called MERLIN that…

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First Patient Dosed in Phase 1b Trial Aiming to Inhibit the Progression of Nonalcoholic Steatohepatitis

Nonalcoholic fatty liver disease (NAFLD) is a condition which causes fat to accumulate in the liver. Nonalcoholic steatohepatitis (NASH) is a severe form of the disease in which the patient also…

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Pliant Announces Phase 1 Clinical Study Evaluating Anti-Fibrotic Agent PLN-74809
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Pliant Announces Phase 1 Clinical Study Evaluating Anti-Fibrotic Agent PLN-74809

Pliant Therapeutics, Inc., a biotechnology company specializing in developing and commercializing treatments for fibrotic diseases, announced on January 3, 2019 through PRNewswire, that it has initiated a Phase 1 first-in-human…

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The FDA has Awarded Over $18 Million for Rare Disease Research
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The FDA has Awarded Over $18 Million for Rare Disease Research

The United States Food and Drug Administration has awarded twelve research grants worth a total of over $18 million for research into rare diseases. For more information about this news,…

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Website to Connect Liver Disease Patients To Clinical Trials
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Website to Connect Liver Disease Patients To Clinical Trials

According to NBC Right Now, the liver disease advocacy organization called The American Liver Foundation is launching an online platform designed to pair liver disease patients to clinical trials. The website,…

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Liver Transplant Saves Two Lives and Creates Bond Between Two Girls
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Liver Transplant Saves Two Lives and Creates Bond Between Two Girls

Kendall and Ava are not related by blood. They do, however, have one amazing thing in common- something that saved their lives and defeated autoimmune hepatitis. Keep reading, or follow…

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