FDA Review Raises Questions About Replimune’s Melanoma Therapy Ahead of Advisory Committee Vote

As reported on Reuters, Replimune’s experimental cancer treatment RP1 is facing increased regulatory scrutiny after U.S. Food and Drug Administration (FDA) reviewers expressed concerns about whether current clinical data adequately…

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Huyabio’s HBI-8000 and Opdivo Combination Shows Significant Benefit in Phase 3 Melanoma Study

As reported on Fierce Pharma, Huyabio has reported encouraging Phase 3 results for its investigational oral HDAC inhibitor, HBI-8000, when used alongside Bristol Myers Squibb’s immunotherapy Opdivo (nivolumab) in patients…

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STUDY: Keytruda + mRNA-4157 (V940) Vaccine Reduced Risk of Severe Melanoma Recurrence
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STUDY: Keytruda + mRNA-4157 (V940) Vaccine Reduced Risk of Severe Melanoma Recurrence

In an investor news release from December 2023, Moderna and Merck shared follow-up data from the Phase 2b KEYNOTE-492/mRNA-4157-P201 clinical trial. During the trial, researchers explored the impact of Keytruda…

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Merkel Cell Carcinoma Has Taken the Life of Jimmy Buffett After Fending Off Cancer for Four Years
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Merkel Cell Carcinoma Has Taken the Life of Jimmy Buffett After Fending Off Cancer for Four Years

  Jimmy Buffett survived a 1994 plane crash that was the inspiration for his song “Live Like It’s Your Last Day." According to an obituary on his website, Jimmy, 76,…

Continue Reading Merkel Cell Carcinoma Has Taken the Life of Jimmy Buffett After Fending Off Cancer for Four Years
Recurrence-Free Survival in High-Risk Stage III Melanoma With Pembrolizumab Confirmed by Long Term Follow-up
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Recurrence-Free Survival in High-Risk Stage III Melanoma With Pembrolizumab Confirmed by Long Term Follow-up

  According to a recent report in the Journal of Clinical Oncology, over one thousand patients with high-risk stage III melanoma were included in the Keynote-054 clinical trial (NCT02362594). The…

Continue Reading Recurrence-Free Survival in High-Risk Stage III Melanoma With Pembrolizumab Confirmed by Long Term Follow-up